by Andrew Kornfeld | Aug 13, 2019 | Biology
Against the Grain Podcast: Dr. Michael Briggs A couple weeks ago I introduced two unsung and unnoticed heroes in the IBD world: Dr. Michael Briggs, a physics professor with Ulcerative Colitis turned unofficial IBD researcher – the author of one of the best and perhaps...
by Andrew Kornfeld | Aug 12, 2019 | Biology
The story of IBD I’m working hard to tell the “story of IBD” and I get a lot of questions about the biological mechanisms of IBD. Here is my belief and understanding of what’s going on: A breakdown of the integrity of the epithelial membrane of...
by Andrew Kornfeld | Jul 24, 2019 | Biology
Could the mitochondria be the next frontier in IBD? The mitochondria are one of the most magnificent structures of the cell. They are the “powerhouses” or the “lungs” of the cell turning the food we eat and the oxygen we breathe into a high energy substrate called...
by Andrew Kornfeld | May 22, 2019 | Biology
Evidence of environmental effects on IBD Evidence points us to understand IBD as a multifactorial process. In most cases, a compounding “perfect storm” comes together to manifest the disease or to worsen symptoms. Genetic predispositions, your gut ecology,...
by Andrew Kornfeld | Apr 19, 2019 | Biology
What is anti-TNF and Tumor Necrosis Factor? Perhaps many of you have heard the term “anti-TNF,” in reference to your medication like Remicade or Humira. What the heck is TNF anyway? Tumor Necrosis Factor (TNF) is a signaling protein in the human...
by Alex Yao | Mar 19, 2019 | Biology
Biology and IBD In order to understand Inflammatory Bowel Disease (IBD), you must understand the biology and some of the systems that make up our body and how they relate to the disease. The First Word In IBD – Inflammatory Inflammation is a defense...